Plasma renin substrate concentration during chronic propranolol therapy.
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چکیده
منابع مشابه
Plasma renin substrate concentration during chronic propranolol therapy.
The review by Gordon 1 concerning a positive correlation between plasma renin substrate concentration (PRS) and blood pressure (BP) prompted us to evaluate our PRS data from a randomized double-blind study on the antihypertensive effect of enalapril (MK 421) compared to propranolol. Twenty-two patients with essential hypertension were treated in subsequent 4-week periods by placebo and 40, 80, ...
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Plasma renin activity is suppressed in approximately 25% of patients with essential hypertension, and the rate of in vitro angiotensin I production after addition of exogenous renin (renin reactivity) is increased in plasma of hypertensive patients. We have recently observed that blood pressure (116 +/- 1.5/68 +/- 1.7 mm Hg) of young women who had hypertension during a first pregnancy 3--6 year...
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1. The results are presented of a cross-sectional study of 25 non-pregnant and 125 pregnant/postnatal women in whom platelet angiotensin II binding and plasma angiotensin II, plasma renin concentration and plasma renin substrate were measured. 2. Platelet angiotensin II binding was significantly lower in the first-trimester patients as compared with the non-pregnant women (P less than 0.001). S...
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Peripheral venous renin activity was determined by the method of Boucher in 15 patients with cirrhosis of the liver and ascites who were on an unrestricted sodium intake. Positive sodium balance was present in all subjects. Marked elevation of mean plasma renin activity (43 ng angiotensin II/min per liter, SD ± 38) was present. The mean plasma renin activity in 16 normal ambulatory subjects on ...
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Aliskiren (Tekturna or Rasilez) is an orally active renin inhibitor approved for the treatment of hypertension.1 As with inhibition of the renin-angiotensin system by angiotensinconverting enzyme inhibitors or type 1 angiotensin II (Ang II) receptor blockers, aliskiren therapy is accompanied by a reactive rise in plasma renin concentration, although in contrast to angiotensin-converting enzyme ...
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ژورنال
عنوان ژورنال: Hypertension
سال: 1984
ISSN: 0194-911X,1524-4563
DOI: 10.1161/01.hyp.6.1.132